Radepur
Brand names,
Radepur
Analogs
Radepur
Brand Names Mixture
- Apo-Chlorax Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
- Corium Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
- Librax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
- Pro Chlorax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
Radepur
Chemical_Formula
C16H14ClN3O
Radepur
RX_link
http://www.rxlist.com/cgi/generic/chlordia.htm
Radepur
fda sheet
Radepur
msds (material safety sheet)
Radepur
Synthesis Reference
No information avaliable
Radepur
Molecular Weight
299.755 g/mol
Radepur
Melting Point
236.2 oC
Radepur
H2O Solubility
2000 mg/L
Radepur
State
Solid
Radepur
LogP
2.853
Radepur
Dosage Forms
Capsule (5 mg, 10 mg or 25 mg)
Radepur
Indication
For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.
Radepur
Pharmacology
Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals.
Radepur
Absorption
No information avaliable
Radepur
side effects and Toxicity
LD50=537 mg/kg (Orally in rats). Signs of overdose include respiratory depression, muscle weakness, somnolence (general depressed activity).
Radepur
Patient Information
Radepur
Organisms Affected
Humans and other mammals