Methaminodiazepoxide
Methaminodiazepoxide Brand names, Methaminodiazepoxide Analogs
- A-Poxide
- Abboxide
- Apo-Chlordiazepoxide
- Balance
- CD 2
- CDO
- CDP
- Chloradiazepoxide
- Chlordiazachel
- Chlordiazepoxid
- Chlordiazepoxide Base
- Chlordiazepoxide Hcl
- Chlordiazepoxidum
- Chloridazepoxide
- Chloridiazepide
- Chloridiazepoxide
- Chlorodiazepoxide
- Chlozepid
- Clopoxide
- Clordiazepossido
- Contol
- Control
- Decacil
- Eden
- Elenium
- Helogaphen
- Ifibrium
- Kalmocaps
- Librax
- Librelease
- Librinin
- Libritabs
- Librium
- Limbitrol
- Limbitrol Ds
- Lygen
- Menrium
- Mesural
- Methaminodiazepoxide
- Mildmen
- Multum
- Napoton
- Napton
- Novo-Poxide
- Psicosan
- Radepur
- Risolid
- Silibrin
- Tropium
- Viopsicol
Methaminodiazepoxide Brand Names Mixture
- Apo-Chlorax Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
- Corium Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
- Librax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
- Pro Chlorax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
Methaminodiazepoxide Chemical_Formula
C16H14ClN3O
Methaminodiazepoxide RX_link
http://www.rxlist.com/cgi/generic/chlordia.htm
Methaminodiazepoxide fda sheet
Methaminodiazepoxide msds (material safety sheet)
Methaminodiazepoxide Synthesis Reference
No information avaliable
Methaminodiazepoxide Molecular Weight
299.755 g/mol
Methaminodiazepoxide Melting Point
236.2 oC
Methaminodiazepoxide H2O Solubility
2000 mg/L
Methaminodiazepoxide State
Solid
Methaminodiazepoxide LogP
2.853
Methaminodiazepoxide Dosage Forms
Capsule (5 mg, 10 mg or 25 mg)
Methaminodiazepoxide Indication
For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.
Methaminodiazepoxide Pharmacology
Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals.
Methaminodiazepoxide Absorption
No information avaliable
Methaminodiazepoxide side effects and Toxicity
LD50=537 mg/kg (Orally in rats). Signs of overdose include respiratory depression, muscle weakness, somnolence (general depressed activity).
Methaminodiazepoxide Patient Information
Methaminodiazepoxide Organisms Affected
Humans and other mammals
