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Helogaphen Brand names, Helogaphen Analogs

Helogaphen Brand Names Mixture

  • Apo-Chlorax Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Corium Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Librax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
  • Pro Chlorax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)

Helogaphen Chemical_Formula


Helogaphen RX_link


Helogaphen fda sheet

Helogaphen msds (material safety sheet)

Helogaphen MSDS

Helogaphen Synthesis Reference

No information avaliable

Helogaphen Molecular Weight

299.755 g/mol

Helogaphen Melting Point

236.2 oC

Helogaphen H2O Solubility

2000 mg/L

Helogaphen State


Helogaphen LogP


Helogaphen Dosage Forms

Capsule (5 mg, 10 mg or 25 mg)

Helogaphen Indication

For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.

Helogaphen Pharmacology

Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals.

Helogaphen Absorption

No information avaliable

Helogaphen side effects and Toxicity

LD50=537 mg/kg (Orally in rats). Signs of overdose include respiratory depression, muscle weakness, somnolence (general depressed activity).

Helogaphen Patient Information

Helogaphen Organisms Affected

Humans and other mammals