Chlorodiazepoxide
Chlorodiazepoxide Brand names, Chlorodiazepoxide Analogs
- A-Poxide
- Abboxide
- Apo-Chlordiazepoxide
- Balance
- CD 2
- CDO
- CDP
- Chloradiazepoxide
- Chlordiazachel
- Chlordiazepoxid
- Chlordiazepoxide Base
- Chlordiazepoxide Hcl
- Chlordiazepoxidum
- Chloridazepoxide
- Chloridiazepide
- Chloridiazepoxide
- Chlorodiazepoxide
- Chlozepid
- Clopoxide
- Clordiazepossido
- Contol
- Control
- Decacil
- Eden
- Elenium
- Helogaphen
- Ifibrium
- Kalmocaps
- Librax
- Librelease
- Librinin
- Libritabs
- Librium
- Limbitrol
- Limbitrol Ds
- Lygen
- Menrium
- Mesural
- Methaminodiazepoxide
- Mildmen
- Multum
- Napoton
- Napton
- Novo-Poxide
- Psicosan
- Radepur
- Risolid
- Silibrin
- Tropium
- Viopsicol
Chlorodiazepoxide Brand Names Mixture
- Apo-Chlorax Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
- Corium Cap (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
- Librax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
- Pro Chlorax (Chlordiazepoxide Hydrochloride + Clidinium Bromide)
Chlorodiazepoxide Chemical_Formula
C16H14ClN3O
Chlorodiazepoxide RX_link
http://www.rxlist.com/cgi/generic/chlordia.htm
Chlorodiazepoxide fda sheet
Chlorodiazepoxide msds (material safety sheet)
Chlorodiazepoxide Synthesis Reference
No information avaliable
Chlorodiazepoxide Molecular Weight
299.755 g/mol
Chlorodiazepoxide Melting Point
236.2 oC
Chlorodiazepoxide H2O Solubility
2000 mg/L
Chlorodiazepoxide State
Solid
Chlorodiazepoxide LogP
2.853
Chlorodiazepoxide Dosage Forms
Capsule (5 mg, 10 mg or 25 mg)
Chlorodiazepoxide Indication
For the management of anxiety disorders or for the short-term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety.
Chlorodiazepoxide Pharmacology
Chlordiazepoxide has antianxiety, sedative, appetite-stimulating and weak analgesic actions. The precise mechanism of action is not known. The drug blocks EEG arousal from stimulation of the brain stem reticular formation. The drug has been studied extensively in many species of animals and these studies are suggestive of action on the limbic system of the brain, which recent evidence indicates is involved in emotional responses. Hostile monkeys were made tame by oral drug doses which did not cause sedation. Chlordiazepoxide revealed a "taming" action with the elimination of fear and aggression. The taming effect of chlordiazepoxide was further demonstrated in rats made vicious by lesions in the septal area of the brain. The drug dosage which effectively blocked the vicious reaction was well below the dose which caused sedation in these animals.
Chlorodiazepoxide Absorption
No information avaliable
Chlorodiazepoxide side effects and Toxicity
LD50=537 mg/kg (Orally in rats). Signs of overdose include respiratory depression, muscle weakness, somnolence (general depressed activity).
Chlorodiazepoxide Patient Information
Chlorodiazepoxide Organisms Affected
Humans and other mammals
