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Procamide Brand names, Procamide Analogs

Procamide Brand Names Mixture

  • No information avaliable

Procamide Chemical_Formula


Procamide RX_link

Procamide fda sheet

Procamide msds (material safety sheet)

Procamide MSDS

Procamide Synthesis Reference

Shannon SK et al., J Comb Chem. 2003 Nov-Dec;5(6):860-8

Procamide Molecular Weight

235.325 g/mol

Procamide Melting Point

165-169 oC

Procamide H2O Solubility

5050 mg/L

Procamide State


Procamide LogP


Procamide Dosage Forms

Capsule; Liquid; Solution; Tablet (extended-release)

Procamide Indication

For the treatment of life-threatening ventricular arrhythmias.

Procamide Pharmacology

Procainamide is an agent indicated for production of local or regional anesthesia and in the treatment of ventricular tachycardia occurring during cardiac manipulation, such as surgery or catheterization, or which may occur during acute myocardial infarction, digitalis toxicity, or other cardiac diseases. The mode of action of the antiarrhythmic effect of Procainamide appears to be similar to that of procaine and quinidine. Ventricular excitability is depressed and the stimulation threshold of the ventricle is increased during diastole. The sinoatrial node is, however, unaffected.

Procamide Absorption

75 to 95%

Procamide side effects and Toxicity

LD50=95 mg/kg (rat, IV); LD50=312 mg/kg (mouse, oral); LD50=103 mg/kg (mouse, IV); LD50=250 mg/kg (rabbit, IV)

Procamide Patient Information

The patient should be encouraged to disclose any past history of drug sensitivity, especially to procaine or other local anesthetic agents, or aspirin, and to report any history of kidney disease, congestive heart failure, myasthenia gravis, liver disease or lupus erythematosus.

The patient should be counseled to report any symptoms of arthralgia, myalgia, fever, chills, skin rash, easy bruising, sore throat or sore mouth, infections, dark urine or icterus, wheezing, muscular weakness, chest or abdominal pain, palpitations, nausea, vomiting, anorexia, diarrhea, hallucinations, dizziness or depression.

Procamide Organisms Affected

Humans and other mammals