Novocamid

Novocamid Brand names, Novocamid Analogs

Novocamid Brand Names Mixture

No information avaliable

Novocamid Chemical_Formula

C₁₃H₂₁N₃O

Novocamid RX_link

http://www.rxlist.com/cgi/generic3/procain.htm

Novocamid fda sheet

Novocamid msds (material safety sheet)

Novocamid MSDS

Novocamid Synthesis Reference

Shannon SK et al., J Comb Chem. 2003 Nov-Dec;5(6):860-8

Novocamid Molecular Weight

235.325 g/mol

Novocamid Melting Point

165-169 ^oC

Novocamid H₂O Solubility

5050 mg/L

Novocamid State

Solid

Novocamid LogP

1.282

Novocamid Dosage Forms

Capsule; Liquid; Solution; Tablet (extended-release)

Novocamid Indication

For the treatment of life-threatening ventricular arrhythmias.

Novocamid Pharmacology

Procainamide is an agent indicated for production of local or regional anesthesia and in the treatment of ventricular tachycardia occurring during cardiac manipulation, such as surgery or catheterization, or which may occur during acute myocardial infarction, digitalis toxicity, or other cardiac diseases. The mode of action of the antiarrhythmic effect of Procainamide appears to be similar to that of procaine and quinidine. Ventricular excitability is depressed and the stimulation threshold of the ventricle is increased during diastole. The sinoatrial node is, however, unaffected.

Novocamid Absorption

75 to 95%

Novocamid side effects and Toxicity

LD₅₀=95 mg/kg (rat, IV); LD₅₀=312 mg/kg (mouse, oral); LD₅₀=103 mg/kg (mouse, IV); LD₅₀=250 mg/kg (rabbit, IV)

Novocamid Patient Information

The patient should be encouraged to disclose any past history of drug sensitivity, especially to procaine or other local anesthetic agents, or aspirin, and to report any history of kidney disease, congestive heart failure, myasthenia gravis, liver disease or lupus erythematosus.

The patient should be counseled to report any symptoms of arthralgia, myalgia, fever, chills, skin rash, easy bruising, sore throat or sore mouth, infections, dark urine or icterus, wheezing, muscular weakness, chest or abdominal pain, palpitations, nausea, vomiting, anorexia, diarrhea, hallucinations, dizziness or depression.

Novocamid Organisms Affected

Humans and other mammals