Procaine Amide en es it fr

Procaine Amide Brand names, Procaine Amide Analogs

Procaine Amide Brand Names Mixture

  • No information avaliable

Procaine Amide Chemical_Formula


Procaine Amide RX_link

Procaine Amide fda sheet

Procaine Amide msds (material safety sheet)

Procaine_Amide MSDS

Procaine Amide Synthesis Reference

Shannon SK et al., J Comb Chem. 2003 Nov-Dec;5(6):860-8

Procaine Amide Molecular Weight

235.325 g/mol

Procaine Amide Melting Point

165-169 oC

Procaine Amide H2O Solubility

5050 mg/L

Procaine Amide State


Procaine Amide LogP


Procaine Amide Dosage Forms

Capsule; Liquid; Solution; Tablet (extended-release)

Procaine Amide Indication

For the treatment of life-threatening ventricular arrhythmias.

Procaine Amide Pharmacology

Procainamide is an agent indicated for production of local or regional anesthesia and in the treatment of ventricular tachycardia occurring during cardiac manipulation, such as surgery or catheterization, or which may occur during acute myocardial infarction, digitalis toxicity, or other cardiac diseases. The mode of action of the antiarrhythmic effect of Procainamide appears to be similar to that of procaine and quinidine. Ventricular excitability is depressed and the stimulation threshold of the ventricle is increased during diastole. The sinoatrial node is, however, unaffected.

Procaine Amide Absorption

75 to 95%

Procaine Amide side effects and Toxicity

LD50=95 mg/kg (rat, IV); LD50=312 mg/kg (mouse, oral); LD50=103 mg/kg (mouse, IV); LD50=250 mg/kg (rabbit, IV)

Procaine Amide Patient Information

The patient should be encouraged to disclose any past history of drug sensitivity, especially to procaine or other local anesthetic agents, or aspirin, and to report any history of kidney disease, congestive heart failure, myasthenia gravis, liver disease or lupus erythematosus.

The patient should be counseled to report any symptoms of arthralgia, myalgia, fever, chills, skin rash, easy bruising, sore throat or sore mouth, infections, dark urine or icterus, wheezing, muscular weakness, chest or abdominal pain, palpitations, nausea, vomiting, anorexia, diarrhea, hallucinations, dizziness or depression.

Procaine Amide Organisms Affected

Humans and other mammals