Novocaine Amide en es it fr

Novocaine Amide Brand names, Novocaine Amide Analogs

Novocaine Amide Brand Names Mixture

  • No information avaliable

Novocaine Amide Chemical_Formula


Novocaine Amide RX_link

Novocaine Amide fda sheet

Novocaine Amide msds (material safety sheet)

Novocaine_Amide MSDS

Novocaine Amide Synthesis Reference

Shannon SK et al., J Comb Chem. 2003 Nov-Dec;5(6):860-8

Novocaine Amide Molecular Weight

235.325 g/mol

Novocaine Amide Melting Point

165-169 oC

Novocaine Amide H2O Solubility

5050 mg/L

Novocaine Amide State


Novocaine Amide LogP


Novocaine Amide Dosage Forms

Capsule; Liquid; Solution; Tablet (extended-release)

Novocaine Amide Indication

For the treatment of life-threatening ventricular arrhythmias.

Novocaine Amide Pharmacology

Procainamide is an agent indicated for production of local or regional anesthesia and in the treatment of ventricular tachycardia occurring during cardiac manipulation, such as surgery or catheterization, or which may occur during acute myocardial infarction, digitalis toxicity, or other cardiac diseases. The mode of action of the antiarrhythmic effect of Procainamide appears to be similar to that of procaine and quinidine. Ventricular excitability is depressed and the stimulation threshold of the ventricle is increased during diastole. The sinoatrial node is, however, unaffected.

Novocaine Amide Absorption

75 to 95%

Novocaine Amide side effects and Toxicity

LD50=95 mg/kg (rat, IV); LD50=312 mg/kg (mouse, oral); LD50=103 mg/kg (mouse, IV); LD50=250 mg/kg (rabbit, IV)

Novocaine Amide Patient Information

The patient should be encouraged to disclose any past history of drug sensitivity, especially to procaine or other local anesthetic agents, or aspirin, and to report any history of kidney disease, congestive heart failure, myasthenia gravis, liver disease or lupus erythematosus.

The patient should be counseled to report any symptoms of arthralgia, myalgia, fever, chills, skin rash, easy bruising, sore throat or sore mouth, infections, dark urine or icterus, wheezing, muscular weakness, chest or abdominal pain, palpitations, nausea, vomiting, anorexia, diarrhea, hallucinations, dizziness or depression.

Novocaine Amide Organisms Affected

Humans and other mammals