Plendil Retard en es it fr

Plendil Retard Brand names, Plendil Retard Analogs

Plendil Retard Brand Names Mixture

  • No information avaliable

Plendil Retard Chemical_Formula


Plendil Retard RX_link

Plendil Retard fda sheet

Plendil_Retard FDA

Plendil Retard msds (material safety sheet)

Plendil Retard Synthesis Reference

P. B. Berntsson et al., U.S. Pat. 4,264,611 (1980)

Plendil Retard Molecular Weight

384.253 g/mol

Plendil Retard Melting Point


Plendil Retard H2O Solubility

19.7 mg/L

Plendil Retard State


Plendil Retard LogP


Plendil Retard Dosage Forms

Oral tablets

Plendil Retard Indication

For the treatment of hypertension

Plendil Retard Pharmacology

Felodipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Felodipine is similar to other peripheral vasodilators. Felodipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes blocking the calcium channels. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Plendil Retard Absorption


Plendil Retard side effects and Toxicity

excessive peripheral vasodilation with marked hypotension and possibly bradycardia

Plendil Retard Patient Information

Information for the Patient

Patients should be instructed to take felodipine whole and not to crush or chew the
tablets. They should be told that mild gingival hyperplasia (gum swelling) has been
reported. Good dental hygiene decreases its incidence and severity.

Note: As with many other drugs, certain advice to patients being treated with felodipine
is warranted. This information is intended to aid in the safe and effective use of this
medication. It is not a disclosure of all possible adverse or intended effects.

Plendil Retard Organisms Affected

Humans and other mammals