Felodur Er en es it fr

Felodur Er Brand names, Felodur Er Analogs

Felodur Er Brand Names Mixture

  • No information avaliable

Felodur Er Chemical_Formula

C18H19Cl2NO4

Felodur Er RX_link

http://www.rxlist.com/cgi/generic2/felo.htm

Felodur Er fda sheet

Felodur_Er FDA

Felodur Er msds (material safety sheet)

Felodur Er Synthesis Reference

P. B. Berntsson et al., U.S. Pat. 4,264,611 (1980)

Felodur Er Molecular Weight

384.253 g/mol

Felodur Er Melting Point

145oC

Felodur Er H2O Solubility

19.7 mg/L

Felodur Er State

Solid

Felodur Er LogP

4.121

Felodur Er Dosage Forms

Oral tablets

Felodur Er Indication

For the treatment of hypertension

Felodur Er Pharmacology

Felodipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Felodipine is similar to other peripheral vasodilators. Felodipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes blocking the calcium channels. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Felodur Er Absorption

15%

Felodur Er side effects and Toxicity

excessive peripheral vasodilation with marked hypotension and possibly bradycardia

Felodur Er Patient Information

Information for the Patient

Patients should be instructed to take felodipine whole and not to crush or chew the
tablets. They should be told that mild gingival hyperplasia (gum swelling) has been
reported. Good dental hygiene decreases its incidence and severity.

Note: As with many other drugs, certain advice to patients being treated with felodipine
is warranted. This information is intended to aid in the safe and effective use of this
medication. It is not a disclosure of all possible adverse or intended effects.

Felodur Er Organisms Affected

Humans and other mammals