Fexofinadine Hcl en es it fr

Fexofinadine Hcl Brand names, Fexofinadine Hcl Analogs

Fexofinadine Hcl Brand Names Mixture

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Fexofinadine Hcl Chemical_Formula


Fexofinadine Hcl RX_link


Fexofinadine Hcl fda sheet

Fexofinadine_Hcl FDA

Fexofinadine Hcl msds (material safety sheet)

Fexofinadine Hcl Synthesis Reference

P. B. Berntsson et al., U.S. Pat. 4,264,611 (1980)

Fexofinadine Hcl Molecular Weight

384.253 g/mol

Fexofinadine Hcl Melting Point


Fexofinadine Hcl H2O Solubility

19.7 mg/L

Fexofinadine Hcl State


Fexofinadine Hcl LogP


Fexofinadine Hcl Dosage Forms

Oral tablets

Fexofinadine Hcl Indication

For the treatment of hypertension

Fexofinadine Hcl Pharmacology

Felodipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Felodipine is similar to other peripheral vasodilators. Felodipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes blocking the calcium channels. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Fexofinadine Hcl Absorption


Fexofinadine Hcl side effects and Toxicity

excessive peripheral vasodilation with marked hypotension and possibly bradycardia

Fexofinadine Hcl Patient Information

Information for the Patient

Patients should be instructed to take felodipine whole and not to crush or chew the
tablets. They should be told that mild gingival hyperplasia (gum swelling) has been
reported. Good dental hygiene decreases its incidence and severity.

Note: As with many other drugs, certain advice to patients being treated with felodipine
is warranted. This information is intended to aid in the safe and effective use of this
medication. It is not a disclosure of all possible adverse or intended effects.

Fexofinadine Hcl Organisms Affected

Humans and other mammals