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Flodil Brand names, Flodil Analogs

Flodil Brand Names Mixture

  • No information avaliable

Flodil Chemical_Formula


Flodil RX_link


Flodil fda sheet

Flodil FDA

Flodil msds (material safety sheet)

Flodil Synthesis Reference

P. B. Berntsson et al., U.S. Pat. 4,264,611 (1980)

Flodil Molecular Weight

384.253 g/mol

Flodil Melting Point


Flodil H2O Solubility

19.7 mg/L

Flodil State


Flodil LogP


Flodil Dosage Forms

Oral tablets

Flodil Indication

For the treatment of hypertension

Flodil Pharmacology

Felodipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Felodipine is similar to other peripheral vasodilators. Felodipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes blocking the calcium channels. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Flodil Absorption


Flodil side effects and Toxicity

excessive peripheral vasodilation with marked hypotension and possibly bradycardia

Flodil Patient Information

Information for the Patient

Patients should be instructed to take felodipine whole and not to crush or chew the
tablets. They should be told that mild gingival hyperplasia (gum swelling) has been
reported. Good dental hygiene decreases its incidence and severity.

Note: As with many other drugs, certain advice to patients being treated with felodipine
is warranted. This information is intended to aid in the safe and effective use of this
medication. It is not a disclosure of all possible adverse or intended effects.

Flodil Organisms Affected

Humans and other mammals