AGON SR en es it fr

AGON SR Brand names, AGON SR Analogs

AGON SR Brand Names Mixture

  • No information avaliable

AGON SR Chemical_Formula

C18H19Cl2NO4

AGON SR RX_link

http://www.rxlist.com/cgi/generic2/felo.htm

AGON SR fda sheet

AGON_SR FDA

AGON SR msds (material safety sheet)

AGON SR Synthesis Reference

P. B. Berntsson et al., U.S. Pat. 4,264,611 (1980)

AGON SR Molecular Weight

384.253 g/mol

AGON SR Melting Point

145oC

AGON SR H2O Solubility

19.7 mg/L

AGON SR State

Solid

AGON SR LogP

4.121

AGON SR Dosage Forms

Oral tablets

AGON SR Indication

For the treatment of hypertension

AGON SR Pharmacology

Felodipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Felodipine is similar to other peripheral vasodilators. Felodipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes blocking the calcium channels. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

AGON SR Absorption

15%

AGON SR side effects and Toxicity

excessive peripheral vasodilation with marked hypotension and possibly bradycardia

AGON SR Patient Information

Information for the Patient

Patients should be instructed to take felodipine whole and not to crush or chew the
tablets. They should be told that mild gingival hyperplasia (gum swelling) has been
reported. Good dental hygiene decreases its incidence and severity.

Note: As with many other drugs, certain advice to patients being treated with felodipine
is warranted. This information is intended to aid in the safe and effective use of this
medication. It is not a disclosure of all possible adverse or intended effects.

AGON SR Organisms Affected

Humans and other mammals