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Penedil Brand names, Penedil Analogs

Penedil Brand Names Mixture

  • No information avaliable

Penedil Chemical_Formula


Penedil RX_link

Penedil fda sheet

Penedil FDA

Penedil msds (material safety sheet)

Penedil Synthesis Reference

P. B. Berntsson et al., U.S. Pat. 4,264,611 (1980)

Penedil Molecular Weight

384.253 g/mol

Penedil Melting Point


Penedil H2O Solubility

19.7 mg/L

Penedil State


Penedil LogP


Penedil Dosage Forms

Oral tablets

Penedil Indication

For the treatment of hypertension

Penedil Pharmacology

Felodipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Felodipine is similar to other peripheral vasodilators. Felodipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes blocking the calcium channels. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Penedil Absorption


Penedil side effects and Toxicity

excessive peripheral vasodilation with marked hypotension and possibly bradycardia

Penedil Patient Information

Information for the Patient

Patients should be instructed to take felodipine whole and not to crush or chew the
tablets. They should be told that mild gingival hyperplasia (gum swelling) has been
reported. Good dental hygiene decreases its incidence and severity.

Note: As with many other drugs, certain advice to patients being treated with felodipine
is warranted. This information is intended to aid in the safe and effective use of this
medication. It is not a disclosure of all possible adverse or intended effects.

Penedil Organisms Affected

Humans and other mammals