Plendil Depottab en es it fr

Plendil Depottab Brand names, Plendil Depottab Analogs

Plendil Depottab Brand Names Mixture

  • No information avaliable

Plendil Depottab Chemical_Formula


Plendil Depottab RX_link

Plendil Depottab fda sheet

Plendil_Depottab FDA

Plendil Depottab msds (material safety sheet)

Plendil Depottab Synthesis Reference

P. B. Berntsson et al., U.S. Pat. 4,264,611 (1980)

Plendil Depottab Molecular Weight

384.253 g/mol

Plendil Depottab Melting Point


Plendil Depottab H2O Solubility

19.7 mg/L

Plendil Depottab State


Plendil Depottab LogP


Plendil Depottab Dosage Forms

Oral tablets

Plendil Depottab Indication

For the treatment of hypertension

Plendil Depottab Pharmacology

Felodipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Felodipine is similar to other peripheral vasodilators. Felodipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes blocking the calcium channels. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Plendil Depottab Absorption


Plendil Depottab side effects and Toxicity

excessive peripheral vasodilation with marked hypotension and possibly bradycardia

Plendil Depottab Patient Information

Information for the Patient

Patients should be instructed to take felodipine whole and not to crush or chew the
tablets. They should be told that mild gingival hyperplasia (gum swelling) has been
reported. Good dental hygiene decreases its incidence and severity.

Note: As with many other drugs, certain advice to patients being treated with felodipine
is warranted. This information is intended to aid in the safe and effective use of this
medication. It is not a disclosure of all possible adverse or intended effects.

Plendil Depottab Organisms Affected

Humans and other mammals