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Oncovin Brand names, Oncovin Analogs

Oncovin Brand Names Mixture

  • No information avaliable

Oncovin Chemical_Formula


Oncovin RX_link


Oncovin fda sheet


Oncovin msds (material safety sheet)

Oncovin MSDS

Oncovin Synthesis Reference

No information avaliable

Oncovin Molecular Weight

824.958 g/mol

Oncovin Melting Point

220 oC

Oncovin H2O Solubility

No information avaliable

Oncovin State


Oncovin LogP


Oncovin Dosage Forms

Liquid; Solution

Oncovin Indication

For treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, acute panmyelosis

Oncovin Pharmacology

Vincristine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vincristine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vincristine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Oncovin Absorption

No information avaliable

Oncovin side effects and Toxicity

IVN-RAT LD50 1300 mg/kg; IPR-MUS LD50 5.2 mg/kg

Oncovin Patient Information


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Oncovin Organisms Affected

Humans and other mammals