Norvasc
Norvasc Brand names, Norvasc Analogs
Norvasc Brand Names Mixture
- Lotrel (amlodipine + benazepril)
Norvasc Chemical_Formula
C20H25ClN2O5
Norvasc RX_link
http://www.rxlist.com/cgi/generic/amlod2.htm
Norvasc fda sheet
Norvasc msds (material safety sheet)
Norvasc Synthesis Reference
S. F. Campbell et al., U.S. Pat. 4,572,909 (1986)
Norvasc Molecular Weight
408.876 g/mol
Norvasc Melting Point
178-179oC
Norvasc H2O Solubility
75.3 mg/L
Norvasc State
Solid
Norvasc LogP
2.347
Norvasc Dosage Forms
Tablets (equivalent to 2.5, 5 and 10 mg)
Norvasc Indication
For the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Norvasc Pharmacology
Amlodipine, a calcium-channel blocker, is used alone or with benazepril, an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Amlodipine is similar to the peripheral vasodilator nifedipine and other members of the dihydropyridine class.
Norvasc Absorption
Amlodipine is slowly and almost completely absorbed from the gastrointestinal tract.
Norvasc side effects and Toxicity
Gross overdosage could result in excessive peripheral vasodilatation and possibly reflex tachycardia. Marked and probably prolonged systemic hypotension up to an including shock with fatal outcome have been reported.
Norvasc Patient Information
Norvasc Organisms Affected
Humans and other mammals
