Amlodipine Free Base
Amlodipine Free Base Brand names, Amlodipine Free Base Analogs
Amlodipine Free Base Brand Names Mixture
- Lotrel (amlodipine + benazepril)
Amlodipine Free Base Chemical_Formula
C20H25ClN2O5
Amlodipine Free Base RX_link
http://www.rxlist.com/cgi/generic/amlod2.htm
Amlodipine Free Base fda sheet
Amlodipine Free Base msds (material safety sheet)
Amlodipine Free Base Synthesis Reference
S. F. Campbell et al., U.S. Pat. 4,572,909 (1986)
Amlodipine Free Base Molecular Weight
408.876 g/mol
Amlodipine Free Base Melting Point
178-179oC
Amlodipine Free Base H2O Solubility
75.3 mg/L
Amlodipine Free Base State
Solid
Amlodipine Free Base LogP
2.347
Amlodipine Free Base Dosage Forms
Tablets (equivalent to 2.5, 5 and 10 mg)
Amlodipine Free Base Indication
For the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Amlodipine Free Base Pharmacology
Amlodipine, a calcium-channel blocker, is used alone or with benazepril, an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Amlodipine is similar to the peripheral vasodilator nifedipine and other members of the dihydropyridine class.
Amlodipine Free Base Absorption
Amlodipine is slowly and almost completely absorbed from the gastrointestinal tract.
Amlodipine Free Base side effects and Toxicity
Gross overdosage could result in excessive peripheral vasodilatation and possibly reflex tachycardia. Marked and probably prolonged systemic hypotension up to an including shock with fatal outcome have been reported.
Amlodipine Free Base Patient Information
Amlodipine Free Base Organisms Affected
Humans and other mammals
