Coroval
Coroval Brand names, Coroval Analogs
Coroval Brand Names Mixture
- Lotrel (amlodipine + benazepril)
Coroval Chemical_Formula
C20H25ClN2O5
Coroval RX_link
http://www.rxlist.com/cgi/generic/amlod2.htm
Coroval fda sheet
Coroval msds (material safety sheet)
Coroval Synthesis Reference
S. F. Campbell et al., U.S. Pat. 4,572,909 (1986)
Coroval Molecular Weight
408.876 g/mol
Coroval Melting Point
178-179oC
Coroval H2O Solubility
75.3 mg/L
Coroval State
Solid
Coroval LogP
2.347
Coroval Dosage Forms
Tablets (equivalent to 2.5, 5 and 10 mg)
Coroval Indication
For the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Coroval Pharmacology
Amlodipine, a calcium-channel blocker, is used alone or with benazepril, an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Amlodipine is similar to the peripheral vasodilator nifedipine and other members of the dihydropyridine class.
Coroval Absorption
Amlodipine is slowly and almost completely absorbed from the gastrointestinal tract.
Coroval side effects and Toxicity
Gross overdosage could result in excessive peripheral vasodilatation and possibly reflex tachycardia. Marked and probably prolonged systemic hypotension up to an including shock with fatal outcome have been reported.
Coroval Patient Information
Coroval Organisms Affected
Humans and other mammals
