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Coroval Brand names, Coroval Analogs

Coroval Brand Names Mixture

  • Lotrel (amlodipine + benazepril)

Coroval Chemical_Formula

C20H25ClN2O5

Coroval RX_link

http://www.rxlist.com/cgi/generic/amlod2.htm

Coroval fda sheet

Coroval msds (material safety sheet)

Coroval Synthesis Reference

S. F. Campbell et al., U.S. Pat. 4,572,909 (1986)

Coroval Molecular Weight

408.876 g/mol

Coroval Melting Point

178-179oC

Coroval H2O Solubility

75.3 mg/L

Coroval State

Solid

Coroval LogP

2.347

Coroval Dosage Forms

Tablets (equivalent to 2.5, 5 and 10 mg)

Coroval Indication

For the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Coroval Pharmacology

Amlodipine, a calcium-channel blocker, is used alone or with benazepril, an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Amlodipine is similar to the peripheral vasodilator nifedipine and other members of the dihydropyridine class.

Coroval Absorption

Amlodipine is slowly and almost completely absorbed from the gastrointestinal tract.

Coroval side effects and Toxicity

Gross overdosage could result in excessive peripheral vasodilatation and possibly reflex tachycardia. Marked and probably prolonged systemic hypotension up to an including shock with fatal outcome have been reported.

Coroval Patient Information

Coroval Organisms Affected

Humans and other mammals