Amlodipine Besilate
Amlodipine Besilate Brand names, Amlodipine Besilate Analogs
Amlodipine Besilate Brand Names Mixture
- Lotrel (amlodipine + benazepril)
Amlodipine Besilate Chemical_Formula
C20H25ClN2O5
Amlodipine Besilate RX_link
http://www.rxlist.com/cgi/generic/amlod2.htm
Amlodipine Besilate fda sheet
Amlodipine Besilate msds (material safety sheet)
Amlodipine Besilate Synthesis Reference
S. F. Campbell et al., U.S. Pat. 4,572,909 (1986)
Amlodipine Besilate Molecular Weight
408.876 g/mol
Amlodipine Besilate Melting Point
178-179oC
Amlodipine Besilate H2O Solubility
75.3 mg/L
Amlodipine Besilate State
Solid
Amlodipine Besilate LogP
2.347
Amlodipine Besilate Dosage Forms
Tablets (equivalent to 2.5, 5 and 10 mg)
Amlodipine Besilate Indication
For the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Amlodipine Besilate Pharmacology
Amlodipine, a calcium-channel blocker, is used alone or with benazepril, an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Amlodipine is similar to the peripheral vasodilator nifedipine and other members of the dihydropyridine class.
Amlodipine Besilate Absorption
Amlodipine is slowly and almost completely absorbed from the gastrointestinal tract.
Amlodipine Besilate side effects and Toxicity
Gross overdosage could result in excessive peripheral vasodilatation and possibly reflex tachycardia. Marked and probably prolonged systemic hypotension up to an including shock with fatal outcome have been reported.
Amlodipine Besilate Patient Information
Amlodipine Besilate Organisms Affected
Humans and other mammals
