Amvaz
Amvaz Brand names, Amvaz Analogs
Amvaz Brand Names Mixture
- Lotrel (amlodipine + benazepril)
Amvaz Chemical_Formula
C20H25ClN2O5
Amvaz RX_link
http://www.rxlist.com/cgi/generic/amlod2.htm
Amvaz fda sheet
Amvaz msds (material safety sheet)
Amvaz Synthesis Reference
S. F. Campbell et al., U.S. Pat. 4,572,909 (1986)
Amvaz Molecular Weight
408.876 g/mol
Amvaz Melting Point
178-179oC
Amvaz H2O Solubility
75.3 mg/L
Amvaz State
Solid
Amvaz LogP
2.347
Amvaz Dosage Forms
Tablets (equivalent to 2.5, 5 and 10 mg)
Amvaz Indication
For the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Amvaz Pharmacology
Amlodipine, a calcium-channel blocker, is used alone or with benazepril, an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Amlodipine is similar to the peripheral vasodilator nifedipine and other members of the dihydropyridine class.
Amvaz Absorption
Amlodipine is slowly and almost completely absorbed from the gastrointestinal tract.
Amvaz side effects and Toxicity
Gross overdosage could result in excessive peripheral vasodilatation and possibly reflex tachycardia. Marked and probably prolonged systemic hypotension up to an including shock with fatal outcome have been reported.
Amvaz Patient Information
Amvaz Organisms Affected
Humans and other mammals
