N1-2-Pyridylsulfanilamide
Brand names,
N1-2-Pyridylsulfanilamide
Analogs
N1-2-Pyridylsulfanilamide
Brand Names Mixture
- Foot Rot Boluses (Ethylenediamine Dihydroiodide + Sulfapyridine)
- Neutral Sulfa 50 (Sulfamethazine + Sulfapyridine + Sulfathiazole)
- Neutral Sulfa 7 (Sulfamethazine + Sulfapyridine + Sulfathiazole)
- Trisulfa G Liq (Sulfamethazine + Sulfapyridine + Sulfathiazole)
N1-2-Pyridylsulfanilamide
Chemical_Formula
C11H11N3O2S
N1-2-Pyridylsulfanilamide
RX_link
No information avaliable
N1-2-Pyridylsulfanilamide
fda sheet
N1-2-Pyridylsulfanilamide
msds (material safety sheet)
N1-2-Pyridylsulfanilamide
Synthesis Reference
No information avaliable
N1-2-Pyridylsulfanilamide
Molecular Weight
249.29 g/mol
N1-2-Pyridylsulfanilamide
Melting Point
192 oC
N1-2-Pyridylsulfanilamide
H2O Solubility
268 mg/L
N1-2-Pyridylsulfanilamide
State
Solid
N1-2-Pyridylsulfanilamide
LogP
2.384
N1-2-Pyridylsulfanilamide
Dosage Forms
Tablet
N1-2-Pyridylsulfanilamide
Indication
For the treatment of dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum
N1-2-Pyridylsulfanilamide
Pharmacology
Sulfapyridine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
N1-2-Pyridylsulfanilamide
Absorption
approximately 60-80%
N1-2-Pyridylsulfanilamide
side effects and Toxicity
ORL-RAT 15800 mg/Kg
N1-2-Pyridylsulfanilamide
Patient Information
PATIENT INFORMATION
Follow the links
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202536.html
http://www.drugs.com/cons/Sulfapyridine.html
N1-2-Pyridylsulfanilamide
Organisms Affected
Humans and other mammals