Plurazol
Plurazol Brand names, Plurazol Analogs
- 2-Sulfanilamidopyridin
- 2-Sulfanilamidopyridine
- 2-Sulfanilylaminopyridine
- 2-Sulfapyridine
- 4-(2-Pyridinylsulfonyl)aniline
- 4-[(2-Pyridylamino)sulfonyl]aniline
- Adiplon
- Coccoclase
- Dagenan
- Eporal
- Eubasin
- Eubasinum
- Haptocil
- M and B 693
- N(sup 1)-2-Pyridylsulfanilamide
- N(sup1)-Pyridylsulfanilamide
- N-2-Pyridylsulfanilamide
- N1-2-Pyridylsulfanilamide
- Piridazol
- Plurazol
- Pyriamid
- Pyridazol
- Relbapiridina
- Ronin
- Septipulmon
- Streptosilpyridine
- Sulfanilamide, N(sup 1)-2-pyridyl-
- Sulfanilamide, N1-2-pyridyl-
- Sulfapyridine (USP)
- Sulfidin
- Sulfidine
- Sulphapyridine
- Thioseptal
- Trianon
Plurazol Brand Names Mixture
- Foot Rot Boluses (Ethylenediamine Dihydroiodide + Sulfapyridine)
- Neutral Sulfa 50 (Sulfamethazine + Sulfapyridine + Sulfathiazole)
- Neutral Sulfa 7 (Sulfamethazine + Sulfapyridine + Sulfathiazole)
- Trisulfa G Liq (Sulfamethazine + Sulfapyridine + Sulfathiazole)
Plurazol Chemical_Formula
C11H11N3O2S
Plurazol RX_link
No information avaliable
Plurazol fda sheet
Plurazol msds (material safety sheet)
Plurazol Synthesis Reference
No information avaliable
Plurazol Molecular Weight
249.29 g/mol
Plurazol Melting Point
192 oC
Plurazol H2O Solubility
268 mg/L
Plurazol State
Solid
Plurazol LogP
2.384
Plurazol Dosage Forms
Tablet
Plurazol Indication
For the treatment of dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum
Plurazol Pharmacology
Sulfapyridine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Plurazol Absorption
approximately 60-80%
Plurazol side effects and Toxicity
ORL-RAT 15800 mg/Kg
Plurazol Patient Information
PATIENT INFORMATION
Follow the links
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202536.html
http://www.drugs.com/cons/Sulfapyridine.html
Follow the links
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202536.html
http://www.drugs.com/cons/Sulfapyridine.html
Plurazol Organisms Affected
Humans and other mammals
