4-[(2-Pyridylamino)sulfonyl]aniline en es it fr

4-[(2-Pyridylamino)sulfonyl]aniline Brand names, 4-[(2-Pyridylamino)sulfonyl]aniline Analogs

4-[(2-Pyridylamino)sulfonyl]aniline Brand Names Mixture

  • Foot Rot Boluses (Ethylenediamine Dihydroiodide + Sulfapyridine)
  • Neutral Sulfa 50 (Sulfamethazine + Sulfapyridine + Sulfathiazole)
  • Neutral Sulfa 7 (Sulfamethazine + Sulfapyridine + Sulfathiazole)
  • Trisulfa G Liq (Sulfamethazine + Sulfapyridine + Sulfathiazole)

4-[(2-Pyridylamino)sulfonyl]aniline Chemical_Formula

C11H11N3O2S

4-[(2-Pyridylamino)sulfonyl]aniline RX_link

No information avaliable

4-[(2-Pyridylamino)sulfonyl]aniline fda sheet

4-[(2-Pyridylamino)sulfonyl]aniline msds (material safety sheet)

4-[(2-Pyridylamino)sulfonyl]aniline MSDS

4-[(2-Pyridylamino)sulfonyl]aniline Synthesis Reference

No information avaliable

4-[(2-Pyridylamino)sulfonyl]aniline Molecular Weight

249.29 g/mol

4-[(2-Pyridylamino)sulfonyl]aniline Melting Point

192 oC

4-[(2-Pyridylamino)sulfonyl]aniline H2O Solubility

268 mg/L

4-[(2-Pyridylamino)sulfonyl]aniline State

Solid

4-[(2-Pyridylamino)sulfonyl]aniline LogP

2.384

4-[(2-Pyridylamino)sulfonyl]aniline Dosage Forms

Tablet

4-[(2-Pyridylamino)sulfonyl]aniline Indication

For the treatment of dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum

4-[(2-Pyridylamino)sulfonyl]aniline Pharmacology

Sulfapyridine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

4-[(2-Pyridylamino)sulfonyl]aniline Absorption

approximately 60-80%

4-[(2-Pyridylamino)sulfonyl]aniline side effects and Toxicity

ORL-RAT 15800 mg/Kg

4-[(2-Pyridylamino)sulfonyl]aniline Patient Information

PATIENT INFORMATION

Follow the links

http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202536.html

http://www.drugs.com/cons/Sulfapyridine.html

4-[(2-Pyridylamino)sulfonyl]aniline Organisms Affected

Humans and other mammals