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Adiplon Brand names, Adiplon Analogs

Adiplon Brand Names Mixture

  • Foot Rot Boluses (Ethylenediamine Dihydroiodide + Sulfapyridine)
  • Neutral Sulfa 50 (Sulfamethazine + Sulfapyridine + Sulfathiazole)
  • Neutral Sulfa 7 (Sulfamethazine + Sulfapyridine + Sulfathiazole)
  • Trisulfa G Liq (Sulfamethazine + Sulfapyridine + Sulfathiazole)

Adiplon Chemical_Formula

C11H11N3O2S

Adiplon RX_link

No information avaliable

Adiplon fda sheet

Adiplon msds (material safety sheet)

Adiplon MSDS

Adiplon Synthesis Reference

No information avaliable

Adiplon Molecular Weight

249.29 g/mol

Adiplon Melting Point

192 oC

Adiplon H2O Solubility

268 mg/L

Adiplon State

Solid

Adiplon LogP

2.384

Adiplon Dosage Forms

Tablet

Adiplon Indication

For the treatment of dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum

Adiplon Pharmacology

Sulfapyridine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Adiplon Absorption

approximately 60-80%

Adiplon side effects and Toxicity

ORL-RAT 15800 mg/Kg

Adiplon Patient Information

PATIENT INFORMATION

Follow the links

http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202536.html

http://www.drugs.com/cons/Sulfapyridine.html

Adiplon Organisms Affected

Humans and other mammals