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Piridazol Brand names, Piridazol Analogs

Piridazol Brand Names Mixture

  • Foot Rot Boluses (Ethylenediamine Dihydroiodide + Sulfapyridine)
  • Neutral Sulfa 50 (Sulfamethazine + Sulfapyridine + Sulfathiazole)
  • Neutral Sulfa 7 (Sulfamethazine + Sulfapyridine + Sulfathiazole)
  • Trisulfa G Liq (Sulfamethazine + Sulfapyridine + Sulfathiazole)

Piridazol Chemical_Formula

C11H11N3O2S

Piridazol RX_link

No information avaliable

Piridazol fda sheet

Piridazol msds (material safety sheet)

Piridazol MSDS

Piridazol Synthesis Reference

No information avaliable

Piridazol Molecular Weight

249.29 g/mol

Piridazol Melting Point

192 oC

Piridazol H2O Solubility

268 mg/L

Piridazol State

Solid

Piridazol LogP

2.384

Piridazol Dosage Forms

Tablet

Piridazol Indication

For the treatment of dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum

Piridazol Pharmacology

Sulfapyridine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Piridazol Absorption

approximately 60-80%

Piridazol side effects and Toxicity

ORL-RAT 15800 mg/Kg

Piridazol Patient Information

PATIENT INFORMATION

Follow the links

http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202536.html

http://www.drugs.com/cons/Sulfapyridine.html

Piridazol Organisms Affected

Humans and other mammals