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Moexipril Brand names, Moexipril Analogs

Moexipril Brand Names Mixture

  • No information avaliable

Moexipril Chemical_Formula


Moexipril RX_link

Moexipril fda sheet

Moexipril msds (material safety sheet)

Moexipril Synthesis Reference

No information avaliable

Moexipril Molecular Weight

498.568 g/mol

Moexipril Melting Point

No information avaliable

Moexipril H2O Solubility

Soluble (about 10% weight-to-volume) in distilled water at room temperature as HCl salt.

Moexipril State


Moexipril LogP


Moexipril Dosage Forms

Tablets (scored, coated, containing 7.5 mg or 15 mg of moexipril hydrochloride for oral administration)

Moexipril Indication

For treatment of patients with hypertension.

Moexipril Pharmacology

Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.

Moexipril Absorption

Moexipril is incompletely absorbed, with bioavailability as moexiprilat of about 13% compared to intravenous (I.V.) moexipril (both measuring the metabolite moexiprilat), and is markedly affected by food, which reduces Cmax and AUC by about 70% and 40% respectively after the ingestion of a low-fat breakfast or by 80% and 50% respectively after the ingestion of a high-fat breakfast.

Moexipril side effects and Toxicity

Human overdoses of moexipril have not been reported. In case reports of overdoses with other ACE inhibitors, hypotension has been the principal adverse effect noted. Single oral doses of 2 g/kg moexipril were associated with significant lethality in mice. Rats, however, tolerated single oral doses of up to 3 g/kg.

Moexipril Patient Information

Moexipril Organisms Affected

Humans and other mammals