Minostate
Minostate Brand names, Minostate Analogs
- Benzoylmetronildazole
- Daktarin
- Femizol-M
- M-zole 3 Combination Pack
- M-zole 7 Dual Pack
- MCZ
- Micatin
- Miconazole 3
- Miconazole 3 Combination Pack
- Miconazole 7
- Miconazole 7 Combination Pack
- Miconazole Nitrate
- Miconazole Nitrate Combination Pack
- Miconazole-7
- Micozole
- Minostate
- Monazole 7
- Monistat
- Monistat 1 Combination Pack
- Monistat 3
- Monistat 3 Combination Pack
- Monistat 3 Dual-Pak
- Monistat 3 Vaginal Ovules
- Monistat 5
- Monistat 5 Tampon
- Monistat 7
- Monistat 7 Combination Pack
- Monistat 7 Dual-Pak
- Monistat 7 Vaginal Suppositories
- Monistat Dual- PAK
- Monistat IV
- Monistat-3 Combination Pack
- Monistat-Derm
- Novo-Miconazole Vaginal Ovules
- Zeasorb-AF
Minostate Brand Names Mixture
- No information avaliable
Minostate Chemical_Formula
C27H34N2O7
Minostate RX_link
http://www.rxlist.com/cgi/generic2/moexip.htm
Minostate fda sheet
Minostate msds (material safety sheet)
Minostate Synthesis Reference
No information avaliable
Minostate Molecular Weight
498.568 g/mol
Minostate Melting Point
No information avaliable
Minostate H2O Solubility
Soluble (about 10% weight-to-volume) in distilled water at room temperature as HCl salt.
Minostate State
Solid
Minostate LogP
3.31
Minostate Dosage Forms
Tablets (scored, coated, containing 7.5 mg or 15 mg of moexipril hydrochloride for oral administration)
Minostate Indication
For treatment of patients with hypertension.
Minostate Pharmacology
Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Minostate Absorption
Moexipril is incompletely absorbed, with bioavailability as moexiprilat of about 13% compared to intravenous (I.V.) moexipril (both measuring the metabolite moexiprilat), and is markedly affected by food, which reduces Cmax and AUC by about 70% and 40% respectively after the ingestion of a low-fat breakfast or by 80% and 50% respectively after the ingestion of a high-fat breakfast.
Minostate side effects and Toxicity
Human overdoses of moexipril have not been reported. In case reports of overdoses with other ACE inhibitors, hypotension has been the principal adverse effect noted. Single oral doses of 2 g/kg moexipril were associated with significant lethality in mice. Rats, however, tolerated single oral doses of up to 3 g/kg.
Minostate Patient Information
Minostate Organisms Affected
Humans and other mammals
