Monistat IV en es it fr

Monistat IV Brand names, Monistat IV Analogs

Monistat IV Brand Names Mixture

  • No information avaliable

Monistat IV Chemical_Formula

C27H34N2O7

Monistat IV RX_link

http://www.rxlist.com/cgi/generic2/moexip.htm

Monistat IV fda sheet

Monistat IV msds (material safety sheet)

Monistat IV Synthesis Reference

No information avaliable

Monistat IV Molecular Weight

498.568 g/mol

Monistat IV Melting Point

No information avaliable

Monistat IV H2O Solubility

Soluble (about 10% weight-to-volume) in distilled water at room temperature as HCl salt.

Monistat IV State

Solid

Monistat IV LogP

3.31

Monistat IV Dosage Forms

Tablets (scored, coated, containing 7.5 mg or 15 mg of moexipril hydrochloride for oral administration)

Monistat IV Indication

For treatment of patients with hypertension.

Monistat IV Pharmacology

Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.

Monistat IV Absorption

Moexipril is incompletely absorbed, with bioavailability as moexiprilat of about 13% compared to intravenous (I.V.) moexipril (both measuring the metabolite moexiprilat), and is markedly affected by food, which reduces Cmax and AUC by about 70% and 40% respectively after the ingestion of a low-fat breakfast or by 80% and 50% respectively after the ingestion of a high-fat breakfast.

Monistat IV side effects and Toxicity

Human overdoses of moexipril have not been reported. In case reports of overdoses with other ACE inhibitors, hypotension has been the principal adverse effect noted. Single oral doses of 2 g/kg moexipril were associated with significant lethality in mice. Rats, however, tolerated single oral doses of up to 3 g/kg.

Monistat IV Patient Information

Monistat IV Organisms Affected

Humans and other mammals