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Micozole Brand names, Micozole Analogs

Micozole Brand Names Mixture

  • No information avaliable

Micozole Chemical_Formula

C27H34N2O7

Micozole RX_link

http://www.rxlist.com/cgi/generic2/moexip.htm

Micozole fda sheet

Micozole msds (material safety sheet)

Micozole Synthesis Reference

No information avaliable

Micozole Molecular Weight

498.568 g/mol

Micozole Melting Point

No information avaliable

Micozole H2O Solubility

Soluble (about 10% weight-to-volume) in distilled water at room temperature as HCl salt.

Micozole State

Solid

Micozole LogP

3.31

Micozole Dosage Forms

Tablets (scored, coated, containing 7.5 mg or 15 mg of moexipril hydrochloride for oral administration)

Micozole Indication

For treatment of patients with hypertension.

Micozole Pharmacology

Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.

Micozole Absorption

Moexipril is incompletely absorbed, with bioavailability as moexiprilat of about 13% compared to intravenous (I.V.) moexipril (both measuring the metabolite moexiprilat), and is markedly affected by food, which reduces Cmax and AUC by about 70% and 40% respectively after the ingestion of a low-fat breakfast or by 80% and 50% respectively after the ingestion of a high-fat breakfast.

Micozole side effects and Toxicity

Human overdoses of moexipril have not been reported. In case reports of overdoses with other ACE inhibitors, hypotension has been the principal adverse effect noted. Single oral doses of 2 g/kg moexipril were associated with significant lethality in mice. Rats, however, tolerated single oral doses of up to 3 g/kg.

Micozole Patient Information

Micozole Organisms Affected

Humans and other mammals