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Cisapride Brand names, Cisapride Analogs

Cisapride Brand Names Mixture

  • No information avaliable

Cisapride Chemical_Formula


Cisapride RX_link

Cisapride fda sheet

Cisapride msds (material safety sheet)

Cisapride MSDS

Cisapride Synthesis Reference

No information avaliable

Cisapride Molecular Weight

465.945 g/mol

Cisapride Melting Point

110 oC

Cisapride H2O Solubility

2.71 mg/L

Cisapride State


Cisapride LogP


Cisapride Dosage Forms

Suspension; Tablet

Cisapride Indication

For the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.

Cisapride Pharmacology

Cisapride is a parasympathomimetic which acts as a serotonin 5-HT4 agonist. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system. Cisapride stimulates motility of the upper gastrointestinal tract without stimulating gastric, biliary, or pancreatic secretions. Cisapride increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. It increases the resting tone of the lower esophageal sphincter. It has little, if any, effect on the motility of the colon or gallbladder. Cisapride does not induce muscarinic or nicotinic receptor stimulation, nor does it inhibit acetylcholinesterase activity.

Cisapride Absorption

Cisapride is rapidly absorbed after oral administration, with an absolute bioavailability of 35-40%.

Cisapride side effects and Toxicity

No information avaliable

Cisapride Patient Information

No information avaliable

Cisapride Organisms Affected

Humans and other mammals