Benzthiazide
Benzthiazide Brand names, Benzthiazide Analogs
Benzthiazide Brand Names Mixture
- No information avaliable
Benzthiazide Chemical_Formula
C15H14ClN3O4S3
Benzthiazide RX_link
No information avaliable
Benzthiazide fda sheet
Benzthiazide msds (material safety sheet)
Benzthiazide Synthesis Reference
No information avaliable
Benzthiazide Molecular Weight
431.94 g/mol
Benzthiazide Melting Point
231.5 oC
Benzthiazide H2O Solubility
8.91 mg/L
Benzthiazide State
Solid
Benzthiazide LogP
2.918
Benzthiazide Dosage Forms
Tablet
Benzthiazide Indication
For the treatment of high blood pressure and management of edema.
Benzthiazide Pharmacology
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Benzthiazide Absorption
Absorbed in the digestive tract.
Benzthiazide side effects and Toxicity
Symptoms of overdose include nausea, vomiting, fatigue, urinary problems and drowsiness.
Benzthiazide Patient Information
Benzthiazide Organisms Affected
Humans and other mammals
