Freeuril
Brand names,
Freeuril
Analogs
Freeuril
Brand Names Mixture
Freeuril
Chemical_Formula
C15H14ClN3O4S3
Freeuril
RX_link
No information avaliable
Freeuril
fda sheet
Freeuril
msds (material safety sheet)
Freeuril
Synthesis Reference
No information avaliable
Freeuril
Molecular Weight
431.94 g/mol
Freeuril
Melting Point
231.5 oC
Freeuril
H2O Solubility
8.91 mg/L
Freeuril
State
Solid
Freeuril
LogP
2.918
Freeuril
Dosage Forms
Tablet
Freeuril
Indication
For the treatment of high blood pressure and management of edema.
Freeuril
Pharmacology
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Freeuril
Absorption
Absorbed in the digestive tract.
Freeuril
side effects and Toxicity
Symptoms of overdose include nausea, vomiting, fatigue, urinary problems and drowsiness.
Freeuril
Patient Information
Freeuril
Organisms Affected
Humans and other mammals