Exosalt
Exosalt Brand names, Exosalt Analogs
Exosalt Brand Names Mixture
- No information avaliable
Exosalt Chemical_Formula
C15H14ClN3O4S3
Exosalt RX_link
No information avaliable
Exosalt fda sheet
Exosalt msds (material safety sheet)
Exosalt Synthesis Reference
No information avaliable
Exosalt Molecular Weight
431.94 g/mol
Exosalt Melting Point
231.5 oC
Exosalt H2O Solubility
8.91 mg/L
Exosalt State
Solid
Exosalt LogP
2.918
Exosalt Dosage Forms
Tablet
Exosalt Indication
For the treatment of high blood pressure and management of edema.
Exosalt Pharmacology
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Exosalt Absorption
Absorbed in the digestive tract.
Exosalt side effects and Toxicity
Symptoms of overdose include nausea, vomiting, fatigue, urinary problems and drowsiness.
Exosalt Patient Information
Exosalt Organisms Affected
Humans and other mammals
