Benzothiazide
Benzothiazide Brand names, Benzothiazide Analogs
Benzothiazide Brand Names Mixture
- No information avaliable
Benzothiazide Chemical_Formula
C15H14ClN3O4S3
Benzothiazide RX_link
No information avaliable
Benzothiazide fda sheet
Benzothiazide msds (material safety sheet)
Benzothiazide Synthesis Reference
No information avaliable
Benzothiazide Molecular Weight
431.94 g/mol
Benzothiazide Melting Point
231.5 oC
Benzothiazide H2O Solubility
8.91 mg/L
Benzothiazide State
Solid
Benzothiazide LogP
2.918
Benzothiazide Dosage Forms
Tablet
Benzothiazide Indication
For the treatment of high blood pressure and management of edema.
Benzothiazide Pharmacology
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Benzothiazide Absorption
Absorbed in the digestive tract.
Benzothiazide side effects and Toxicity
Symptoms of overdose include nausea, vomiting, fatigue, urinary problems and drowsiness.
Benzothiazide Patient Information
Benzothiazide Organisms Affected
Humans and other mammals
