Dihydrex
Dihydrex Brand names, Dihydrex Analogs
Dihydrex Brand Names Mixture
- No information avaliable
Dihydrex Chemical_Formula
C15H14ClN3O4S3
Dihydrex RX_link
No information avaliable
Dihydrex fda sheet
Dihydrex msds (material safety sheet)
Dihydrex Synthesis Reference
No information avaliable
Dihydrex Molecular Weight
431.94 g/mol
Dihydrex Melting Point
231.5 oC
Dihydrex H2O Solubility
8.91 mg/L
Dihydrex State
Solid
Dihydrex LogP
2.918
Dihydrex Dosage Forms
Tablet
Dihydrex Indication
For the treatment of high blood pressure and management of edema.
Dihydrex Pharmacology
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Dihydrex Absorption
Absorbed in the digestive tract.
Dihydrex side effects and Toxicity
Symptoms of overdose include nausea, vomiting, fatigue, urinary problems and drowsiness.
Dihydrex Patient Information
Dihydrex Organisms Affected
Humans and other mammals
