Lemazide
Lemazide Brand names, Lemazide Analogs
Lemazide Brand Names Mixture
- No information avaliable
Lemazide Chemical_Formula
C15H14ClN3O4S3
Lemazide RX_link
No information avaliable
Lemazide fda sheet
Lemazide msds (material safety sheet)
Lemazide Synthesis Reference
No information avaliable
Lemazide Molecular Weight
431.94 g/mol
Lemazide Melting Point
231.5 oC
Lemazide H2O Solubility
8.91 mg/L
Lemazide State
Solid
Lemazide LogP
2.918
Lemazide Dosage Forms
Tablet
Lemazide Indication
For the treatment of high blood pressure and management of edema.
Lemazide Pharmacology
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Lemazide Absorption
Absorbed in the digestive tract.
Lemazide side effects and Toxicity
Symptoms of overdose include nausea, vomiting, fatigue, urinary problems and drowsiness.
Lemazide Patient Information
Lemazide Organisms Affected
Humans and other mammals
