Aquatag
Brand names,
Aquatag
Analogs
Aquatag
Brand Names Mixture
Aquatag
Chemical_Formula
C15H14ClN3O4S3
Aquatag
RX_link
No information avaliable
Aquatag
fda sheet
Aquatag
msds (material safety sheet)
Aquatag
Synthesis Reference
No information avaliable
Aquatag
Molecular Weight
431.94 g/mol
Aquatag
Melting Point
231.5 oC
Aquatag
H2O Solubility
8.91 mg/L
Aquatag
State
Solid
Aquatag
LogP
2.918
Aquatag
Dosage Forms
Tablet
Aquatag
Indication
For the treatment of high blood pressure and management of edema.
Aquatag
Pharmacology
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Aquatag
Absorption
Absorbed in the digestive tract.
Aquatag
side effects and Toxicity
Symptoms of overdose include nausea, vomiting, fatigue, urinary problems and drowsiness.
Aquatag
Patient Information
Aquatag
Organisms Affected
Humans and other mammals