Fovane
Brand names,
Fovane
Analogs
Fovane
Brand Names Mixture
Fovane
Chemical_Formula
C15H14ClN3O4S3
Fovane
RX_link
No information avaliable
Fovane
fda sheet
Fovane
msds (material safety sheet)
Fovane
Synthesis Reference
No information avaliable
Fovane
Molecular Weight
431.94 g/mol
Fovane
Melting Point
231.5 oC
Fovane
H2O Solubility
8.91 mg/L
Fovane
State
Solid
Fovane
LogP
2.918
Fovane
Dosage Forms
Tablet
Fovane
Indication
For the treatment of high blood pressure and management of edema.
Fovane
Pharmacology
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Fovane
Absorption
Absorbed in the digestive tract.
Fovane
side effects and Toxicity
Symptoms of overdose include nausea, vomiting, fatigue, urinary problems and drowsiness.
Fovane
Patient Information
Fovane
Organisms Affected
Humans and other mammals