Edemex
Brand names,
Edemex
Analogs
Edemex
Brand Names Mixture
Edemex
Chemical_Formula
C15H14ClN3O4S3
Edemex
RX_link
No information avaliable
Edemex
fda sheet
Edemex
msds (material safety sheet)
Edemex
Synthesis Reference
No information avaliable
Edemex
Molecular Weight
431.94 g/mol
Edemex
Melting Point
231.5 oC
Edemex
H2O Solubility
8.91 mg/L
Edemex
State
Solid
Edemex
LogP
2.918
Edemex
Dosage Forms
Tablet
Edemex
Indication
For the treatment of high blood pressure and management of edema.
Edemex
Pharmacology
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Edemex
Absorption
Absorbed in the digestive tract.
Edemex
side effects and Toxicity
Symptoms of overdose include nausea, vomiting, fatigue, urinary problems and drowsiness.
Edemex
Patient Information
Edemex
Organisms Affected
Humans and other mammals