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Top form wormer Brand names, Top form wormer Analogs

Top form wormer Brand Names Mixture

  • No information avaliable

Top form wormer Chemical_Formula

C11H16N2O

Top form wormer RX_link

http://www.rxlist.com/cgi/generic3/tocainide.htm

Top form wormer fda sheet

Top form wormer msds (material safety sheet)

Top form wormer Synthesis Reference

No information avaliable

Top form wormer Molecular Weight

192.258 g/mol

Top form wormer Melting Point

246-266 oC

Top form wormer H2O Solubility

1.07E+004 mg/L

Top form wormer State

Solid

Top form wormer LogP

1.308

Top form wormer Dosage Forms

400 mg and 600 mg tablets for oral administration

Top form wormer Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Top form wormer Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Top form wormer Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Top form wormer side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Top form wormer Patient Information

Top form wormer Organisms Affected

Humans and other mammals