Tiabendazole en es it fr

Tiabendazole Brand names, Tiabendazole Analogs

Tiabendazole Brand Names Mixture

  • No information avaliable

Tiabendazole Chemical_Formula

C11H16N2O

Tiabendazole RX_link

http://www.rxlist.com/cgi/generic3/tocainide.htm

Tiabendazole fda sheet

Tiabendazole msds (material safety sheet)

Tiabendazole Synthesis Reference

No information avaliable

Tiabendazole Molecular Weight

192.258 g/mol

Tiabendazole Melting Point

246-266 oC

Tiabendazole H2O Solubility

1.07E+004 mg/L

Tiabendazole State

Solid

Tiabendazole LogP

1.308

Tiabendazole Dosage Forms

400 mg and 600 mg tablets for oral administration

Tiabendazole Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Tiabendazole Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Tiabendazole Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Tiabendazole side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Tiabendazole Patient Information

Tiabendazole Organisms Affected

Humans and other mammals