Hokustar hp

Hokustar hp Brand names, Hokustar hp Analogs

Hokustar hp Brand Names Mixture

No information avaliable

Hokustar hp Chemical_Formula

C₁₁H₁₆N₂O

Hokustar hp RX_link

http://www.rxlist.com/cgi/generic3/tocainide.htm

Hokustar hp fda sheet

Hokustar hp msds (material safety sheet)

Hokustar hp Synthesis Reference

No information avaliable

Hokustar hp Molecular Weight

192.258 g/mol

Hokustar hp Melting Point

246-266 ^oC

Hokustar hp H₂O Solubility

1.07E+004 mg/L

Hokustar hp State

Solid

Hokustar hp LogP

1.308

Hokustar hp Dosage Forms

400 mg and 600 mg tablets for oral administration

Hokustar hp Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Hokustar hp Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Hokustar hp Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Hokustar hp side effects and Toxicity

The oral LD₅₀ of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Hokustar hp Patient Information

Hokustar hp Organisms Affected

Humans and other mammals