Tecto 60

Tecto 60 Brand names, Tecto 60 Analogs

Tecto 60 Brand Names Mixture

No information avaliable

Tecto 60 Chemical_Formula

C₁₁H₁₆N₂O

Tecto 60 RX_link

http://www.rxlist.com/cgi/generic3/tocainide.htm

Tecto 60 fda sheet

Tecto 60 msds (material safety sheet)

Tecto 60 Synthesis Reference

No information avaliable

Tecto 60 Molecular Weight

192.258 g/mol

Tecto 60 Melting Point

246-266 ^oC

Tecto 60 H₂O Solubility

1.07E+004 mg/L

Tecto 60 State

Solid

Tecto 60 LogP

1.308

Tecto 60 Dosage Forms

400 mg and 600 mg tablets for oral administration

Tecto 60 Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Tecto 60 Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Tecto 60 Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Tecto 60 side effects and Toxicity

The oral LD₅₀ of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Tecto 60 Patient Information

Tecto 60 Organisms Affected

Humans and other mammals