Chemviron TK 100

Chemviron TK 100 Brand names, Chemviron TK 100 Analogs

Chemviron TK 100 Brand Names Mixture

No information avaliable

Chemviron TK 100 Chemical_Formula

C₁₁H₁₆N₂O

Chemviron TK 100 RX_link

http://www.rxlist.com/cgi/generic3/tocainide.htm

Chemviron TK 100 fda sheet

Chemviron TK 100 msds (material safety sheet)

Chemviron TK 100 Synthesis Reference

No information avaliable

Chemviron TK 100 Molecular Weight

192.258 g/mol

Chemviron TK 100 Melting Point

246-266 ^oC

Chemviron TK 100 H₂O Solubility

1.07E+004 mg/L

Chemviron TK 100 State

Solid

Chemviron TK 100 LogP

1.308

Chemviron TK 100 Dosage Forms

400 mg and 600 mg tablets for oral administration

Chemviron TK 100 Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Chemviron TK 100 Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Chemviron TK 100 Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Chemviron TK 100 side effects and Toxicity

The oral LD₅₀ of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Chemviron TK 100 Patient Information

Chemviron TK 100 Organisms Affected

Humans and other mammals