PharmacyCodes



Mertect 160 en es it fr

Mertect 160 Brand names, Mertect 160 Analogs

Mertect 160 Brand Names Mixture

  • No information avaliable

Mertect 160 Chemical_Formula

C11H16N2O

Mertect 160 RX_link

http://www.rxlist.com/cgi/generic3/tocainide.htm

Mertect 160 fda sheet

Mertect 160 msds (material safety sheet)

Mertect 160 Synthesis Reference

No information avaliable

Mertect 160 Molecular Weight

192.258 g/mol

Mertect 160 Melting Point

246-266 oC

Mertect 160 H2O Solubility

1.07E+004 mg/L

Mertect 160 State

Solid

Mertect 160 LogP

1.308

Mertect 160 Dosage Forms

400 mg and 600 mg tablets for oral administration

Mertect 160 Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Mertect 160 Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Mertect 160 Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Mertect 160 side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Mertect 160 Patient Information

Mertect 160 Organisms Affected

Humans and other mammals