PharmacyCodes



Tecto 40F en es it fr

Tecto 40F Brand names, Tecto 40F Analogs

Tecto 40F Brand Names Mixture

  • No information avaliable

Tecto 40F Chemical_Formula

C11H16N2O

Tecto 40F RX_link

http://www.rxlist.com/cgi/generic3/tocainide.htm

Tecto 40F fda sheet

Tecto 40F msds (material safety sheet)

Tecto 40F Synthesis Reference

No information avaliable

Tecto 40F Molecular Weight

192.258 g/mol

Tecto 40F Melting Point

246-266 oC

Tecto 40F H2O Solubility

1.07E+004 mg/L

Tecto 40F State

Solid

Tecto 40F LogP

1.308

Tecto 40F Dosage Forms

400 mg and 600 mg tablets for oral administration

Tecto 40F Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Tecto 40F Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Tecto 40F Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Tecto 40F side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Tecto 40F Patient Information

Tecto 40F Organisms Affected

Humans and other mammals