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Pasolac Brand names, Pasolac Analogs

Pasolac Brand Names Mixture

  • No information avaliable

Pasolac Chemical_Formula

C7H7NO3

Pasolac RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

Pasolac fda sheet

Pasolac msds (material safety sheet)

Pasolac MSDS

Pasolac Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Pasolac Molecular Weight

153.135 g/mol

Pasolac Melting Point

150.5 oC

Pasolac H2O Solubility

1690 mg/L

Pasolac State

Solid

Pasolac LogP

1.012

Pasolac Dosage Forms

Packet of coated granules

Pasolac Indication

For the treatment of tuberculosis

Pasolac Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Pasolac Absorption

No information avaliable

Pasolac side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

Pasolac Patient Information

Pasolac Organisms Affected

Mycobacteria