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Pasara Brand names, Pasara Analogs

Pasara Brand Names Mixture

  • No information avaliable

Pasara Chemical_Formula

C7H7NO3

Pasara RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

Pasara fda sheet

Pasara msds (material safety sheet)

Pasara MSDS

Pasara Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Pasara Molecular Weight

153.135 g/mol

Pasara Melting Point

150.5 oC

Pasara H2O Solubility

1690 mg/L

Pasara State

Solid

Pasara LogP

1.012

Pasara Dosage Forms

Packet of coated granules

Pasara Indication

For the treatment of tuberculosis

Pasara Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Pasara Absorption

No information avaliable

Pasara side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

Pasara Patient Information

Pasara Organisms Affected

Mycobacteria