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Pamisyl Brand names, Pamisyl Analogs

Pamisyl Brand Names Mixture

  • No information avaliable

Pamisyl Chemical_Formula

C7H7NO3

Pamisyl RX_link

http://www.rxlist.com/cgi/generic2/paser.htm

Pamisyl fda sheet

Pamisyl msds (material safety sheet)

Pamisyl MSDS

Pamisyl Synthesis Reference

Biniecki S., et al. Acta Pol Pharm. 1967;24(5):469-73

Pamisyl Molecular Weight

153.135 g/mol

Pamisyl Melting Point

150.5 oC

Pamisyl H2O Solubility

1690 mg/L

Pamisyl State

Solid

Pamisyl LogP

1.012

Pamisyl Dosage Forms

Packet of coated granules

Pamisyl Indication

For the treatment of tuberculosis

Pamisyl Pharmacology

Aminosalicylic acid is an anti-mycobacterial agent used with other anti-tuberculosis drugs (most often isoniazid) for the treatment of all forms of active tuberculosis due to susceptible strains of tubercle bacilli. The two major considerations in the clinical pharmacology of aminosalicylic acid are the prompt production of a toxic inactive metabolite under acid conditions and the short serum half life of one hour for the free drug. Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis (prevents the multiplying of bacteria without destroying them). It also inhibits the onset of bacterial resistance to streptomycin and isoniazid.

Pamisyl Absorption

No information avaliable

Pamisyl side effects and Toxicity

LD50=4 gm/kg (orally in mice); LD50=3650 mg/kg (orally in rabbits)

Pamisyl Patient Information

Pamisyl Organisms Affected

Mycobacteria